Conserved kappa B element located downstream of the tumor necrosis factor alpha gene: distinct NF-kappa B binding pattern and enhancer activity in LPS activated murine macrophages.

Transcriptional activation of various genes by lipopolysaccharide (LPS) is known to be mediated, at least in part, by the NF-kappa B/Rel family of transcription factors. We have identified a novel kappa B element located immediately downstream of the TNF-alpha gene that is conserved together with it...

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Autors principals: Kuprash, D, Udalova, I, Turetskaya, R, Rice, N, Nedospasov, SA
Format: Journal article
Idioma:English
Publicat: 1995