Androgens target prohibitin to regulate proliferation of prostate cancer cells.
Proteins involved in the growth response of prostate cancer cells to androgen were investigated by comparing the proteomes of LNCaP cells treated with vehicle or androgen. Whole-cell lysates were separated by two-dimensional PAGE, and HPLC-MS/MS was used to identify androgen-regulated proteins. Proh...
Autori principali: | Gamble, S, Odontiadis, M, Waxman, J, Westbrook, J, Dunn, M, Wait, R, Lam, E, Bevan, C |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2004
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