Preoperative atorvastatin treatment in CABG patients rapidly improves vein graft redox state by inhibition of Rac1 and NADPH-oxidase activity.

Preoperative atorvastatin treatment in CABG patients rapidly improves vein graft redox state by inhibition of Rac1 and NADPH-oxidase activity.

BACKGROUND: Statins improve clinical outcome of patients with atherosclerosis, but their perioperative role in patients undergoing coronary artery bypass grafting (CABG) is unclear. We hypothesized that short-term treatment with atorvastatin before CABG would improve the redox state in saphenous ve...

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Bibliographic Details
Main Authors: Antoniades, C, Bakogiannis, C, Tousoulis, D, Reilly, S, Zhang, M, Paschalis, A, Antonopoulos, A, Demosthenous, M, Miliou, A, Psarros, C, Marinou, K, Sfyras, N, Economopoulos, G, Casadei, B, Channon, K, Stefanadis, C
Format: Journal article
Language:English
Published: 2010

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