Equilibration in bicyclic pyroglutamates by ring opening-reclosure
Enantiopure bicyclic tetramates, readily obtained by Dieckmann ring closure on oxazolidine-derived templates, can be further converted to hydroxypyroglutamates by kinetically controlled nucleophilic additions, and some of these products are capable of equilibration via a facile retro-aldol/aldol rec...
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| Format: | Journal article |
| Sprog: | English |
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2008
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| _version_ | 1826270299680669696 |
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| author | Moloney, M Yaqoob, M |
| author_facet | Moloney, M Yaqoob, M |
| author_sort | Moloney, M |
| collection | OXFORD |
| description | Enantiopure bicyclic tetramates, readily obtained by Dieckmann ring closure on oxazolidine-derived templates, can be further converted to hydroxypyroglutamates by kinetically controlled nucleophilic additions, and some of these products are capable of equilibration via a facile retro-aldol/aldol reclosure. © 2008 Elsevier Ltd. All rights reserved. |
| first_indexed | 2024-03-06T21:38:41Z |
| format | Journal article |
| id | oxford-uuid:4723f32e-14b1-4269-b893-ab69a2bf18ee |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:38:41Z |
| publishDate | 2008 |
| record_format | dspace |
| spelling | oxford-uuid:4723f32e-14b1-4269-b893-ab69a2bf18ee2022-03-26T15:18:17ZEquilibration in bicyclic pyroglutamates by ring opening-reclosureJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4723f32e-14b1-4269-b893-ab69a2bf18eeEnglishSymplectic Elements at Oxford2008Moloney, MYaqoob, MEnantiopure bicyclic tetramates, readily obtained by Dieckmann ring closure on oxazolidine-derived templates, can be further converted to hydroxypyroglutamates by kinetically controlled nucleophilic additions, and some of these products are capable of equilibration via a facile retro-aldol/aldol reclosure. © 2008 Elsevier Ltd. All rights reserved. |
| spellingShingle | Moloney, M Yaqoob, M Equilibration in bicyclic pyroglutamates by ring opening-reclosure |
| title | Equilibration in bicyclic pyroglutamates by ring opening-reclosure |
| title_full | Equilibration in bicyclic pyroglutamates by ring opening-reclosure |
| title_fullStr | Equilibration in bicyclic pyroglutamates by ring opening-reclosure |
| title_full_unstemmed | Equilibration in bicyclic pyroglutamates by ring opening-reclosure |
| title_short | Equilibration in bicyclic pyroglutamates by ring opening-reclosure |
| title_sort | equilibration in bicyclic pyroglutamates by ring opening reclosure |
| work_keys_str_mv | AT moloneym equilibrationinbicyclicpyroglutamatesbyringopeningreclosure AT yaqoobm equilibrationinbicyclicpyroglutamatesbyringopeningreclosure |