Galectin-3 is an amplifier of inflammation in atherosclerotic plaque progression through macrophage activation and monocyte chemoattraction.

Galectin-3 is an amplifier of inflammation in atherosclerotic plaque progression through macrophage activation and monocyte chemoattraction.

OBJECTIVE: Galectin-3 (Gal-3) is a 26-kDa lectin known to regulate many aspects of inflammatory cell behavior. We assessed the hypothesis that increased levels of Gal-3 contribute to atherosclerotic plaque progression by enhancing monocyte chemoattraction through macrophage activation. METHODS AND...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Papaspyridonos, M, McNeill, E, de Bono, J, Smith, A, Burnand, K, Channon, K, Greaves, D
Format:	Journal article
Sprog:	English
Udgivet:	2008

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