Subunit architecture of multiprotein assemblies determined using restraints from gas-phase measurements.

Protein interaction networks are becoming an increasingly important area of research within structural genomics. Here we present an ion mobility-mass spectrometry approach capable of distinguishing the overall subunit architecture of protein complexes. The approach relies on the simultaneous measure...

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Hlavní autoři: Pukala, T, Ruotolo, B, Zhou, M, Politis, A, Stefanescu, R, Leary, J, Robinson, C
Médium: Journal article
Jazyk:English
Vydáno: 2009