Poly-l-glutamic acid derivatives as vectors for gene therapy

<p style="text-align:justify;"> This paper describes the synthesis and evaluation of biodegradable derivatives of poly-l-glutamic acid as suitable vectors for gene therapy. When mixed with DNA the new polymers self assemble and form polyelectrolyte complexes. The formation of the co...

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Detalhes bibliográficos
Principais autores: Dekie, L, Toncheva, V, Dubruel, P, Schacht, E, Barrett, L, Seymour, L
Formato: Journal article
Publicado em: Elsevier 2000