In search of a ‘pan-European value set’; application for EQ-5D-3L
<p><strong>Objectives</strong> Country-specific value sets for the EQ-5D are available which reflect preferences for health states elicited from the general population. This allows the transformation of responses on EQ-5D to health state utility values. Only twelve European countri...
| Main Authors: | , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
BioMed Central
2023
|
| _version_ | 1797111162614054912 |
|---|---|
| author | Sajjad, A Versteegh, MM Santi, I Busschbach, J Simon, J Roijen, LH-V |
| author_facet | Sajjad, A Versteegh, MM Santi, I Busschbach, J Simon, J Roijen, LH-V |
| author_sort | Sajjad, A |
| collection | OXFORD |
| description | <p><strong>Objectives</strong> Country-specific value sets for the EQ-5D are available which reflect preferences for health states elicited from the general population. This allows the transformation of responses on EQ-5D to health state utility values. Only twelve European countries possess country-specific value sets and no value set reflecting the preferences of Europe exists. We aim to estimate a ‘pan-European’ value set for the EQ-5D-3L, reflecting the preferences for health states of the European population that could help to evaluate health care from the perspective of the European decision-maker.</p>
<p><strong>Methods</strong> We systematically assessed and compared the methodologies of available EQ-5D-3L time trade-off (TTO) value sets from twelve European countries: Denmark, France, Germany, Hungary, Italy, Netherlands, Poland, Portugal, Romania, Slovenia, Spain and UK. Using their published coefficients, a dataset with utility values for all 243 health states was simulated. Different modelling techniques and model specifications including interaction terms were tested. Model selection was based on goodness-of-fit criteria. We also explored results with application of population size weights.</p>
<p><strong>Results</strong> Methodological, procedural and analytical characteristics of the included EQ-5D-3L valuation studies were quite comparable. An OLS based model was the preferred model to represent European preferences. Weighting with population size made little difference.</p>
<p><strong>Conclusions</strong> EQ-5D-3L valuation studies were considered of sufficient comparability to form the basis for a new ‘pan-European’ value set. The method used allows for an easy update when new national value sets become available.</p> |
| first_indexed | 2024-03-07T08:04:54Z |
| format | Journal article |
| id | oxford-uuid:474c2c92-bdfc-42a6-bb97-d384c486f827 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T08:04:54Z |
| publishDate | 2023 |
| publisher | BioMed Central |
| record_format | dspace |
| spelling | oxford-uuid:474c2c92-bdfc-42a6-bb97-d384c486f8272023-10-26T10:49:12ZIn search of a ‘pan-European value set’; application for EQ-5D-3LJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:474c2c92-bdfc-42a6-bb97-d384c486f827EnglishSymplectic ElementsBioMed Central2023Sajjad, AVersteegh, MMSanti, IBusschbach, JSimon, JRoijen, LH-V<p><strong>Objectives</strong> Country-specific value sets for the EQ-5D are available which reflect preferences for health states elicited from the general population. This allows the transformation of responses on EQ-5D to health state utility values. Only twelve European countries possess country-specific value sets and no value set reflecting the preferences of Europe exists. We aim to estimate a ‘pan-European’ value set for the EQ-5D-3L, reflecting the preferences for health states of the European population that could help to evaluate health care from the perspective of the European decision-maker.</p> <p><strong>Methods</strong> We systematically assessed and compared the methodologies of available EQ-5D-3L time trade-off (TTO) value sets from twelve European countries: Denmark, France, Germany, Hungary, Italy, Netherlands, Poland, Portugal, Romania, Slovenia, Spain and UK. Using their published coefficients, a dataset with utility values for all 243 health states was simulated. Different modelling techniques and model specifications including interaction terms were tested. Model selection was based on goodness-of-fit criteria. We also explored results with application of population size weights.</p> <p><strong>Results</strong> Methodological, procedural and analytical characteristics of the included EQ-5D-3L valuation studies were quite comparable. An OLS based model was the preferred model to represent European preferences. Weighting with population size made little difference.</p> <p><strong>Conclusions</strong> EQ-5D-3L valuation studies were considered of sufficient comparability to form the basis for a new ‘pan-European’ value set. The method used allows for an easy update when new national value sets become available.</p> |
| spellingShingle | Sajjad, A Versteegh, MM Santi, I Busschbach, J Simon, J Roijen, LH-V In search of a ‘pan-European value set’; application for EQ-5D-3L |
| title | In search of a ‘pan-European value set’; application for EQ-5D-3L |
| title_full | In search of a ‘pan-European value set’; application for EQ-5D-3L |
| title_fullStr | In search of a ‘pan-European value set’; application for EQ-5D-3L |
| title_full_unstemmed | In search of a ‘pan-European value set’; application for EQ-5D-3L |
| title_short | In search of a ‘pan-European value set’; application for EQ-5D-3L |
| title_sort | in search of a pan european value set application for eq 5d 3l |
| work_keys_str_mv | AT sajjada insearchofapaneuropeanvaluesetapplicationforeq5d3l AT versteeghmm insearchofapaneuropeanvaluesetapplicationforeq5d3l AT santii insearchofapaneuropeanvaluesetapplicationforeq5d3l AT busschbachj insearchofapaneuropeanvaluesetapplicationforeq5d3l AT simonj insearchofapaneuropeanvaluesetapplicationforeq5d3l AT roijenlhv insearchofapaneuropeanvaluesetapplicationforeq5d3l |