Hyperpolarized magnetic resonance shows that the antiischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved postischemic function in the diabetic heart

Míreanna comhchosúla

• Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized MRS
  de réir: Timm, KN, et al.
  Foilsithe / Cruthaithe: (2018)
• In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance.
  de réir: Schroeder, M, et al.
  Foilsithe / Cruthaithe: (2008)
• Simultaneous investigation of cardiac pyruvate dehydrogenase flux, Krebs cycle metabolism and pH, using hyperpolarized [1,2- C ]pyruvate in vivo
  de réir: Chen, A, et al.
  Foilsithe / Cruthaithe: (2012)
• L-Carnitine stimulates in vivo carbohydrate metabolism in the Type 1 diabetic heart as demonstrated by hyperpolarized MRI
  de réir: Savic, D, et al.
  Foilsithe / Cruthaithe: (2021)
• Simultaneous investigation of cardiac pyruvate dehydrogenase flux, Krebs cycle metabolism and pH, using hyperpolarized [1,2-(13)C2]pyruvate in vivo.
  de réir: Chen, A, et al.
  Foilsithe / Cruthaithe: (2012)