Epithelial cell intrinsic and extrinsic effects of WNT disruption in colorectal tumorigenesis
Despite cancer initiation being attributed to specific pools of epithelial stem cells, tumorigenic transformation is a complex process that entails the co-evolution of the epithelial and stromal compartments. Here, I studied how the stem cell composition of a given malignancy shapes the interactions...
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| Format: | Thesis |
| Language: | English |
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2021
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