Studies on side chain interactions during the isopenicillin N synthase catalysed biosynthesis of penicillins
The role of the L-δ-(α-aminoadipoyl)-L-cysteinyl amide bond in isopenicillin N synthase catalysis is probed by the synthesis of two analogues of its tripeptide substrate L-δ-α-aminoadipoyl-L-cysteinyl-D-valine.
| Hoofdauteurs: | , , , |
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| Formaat: | Journal article |
| Taal: | English |
| Gepubliceerd in: |
1997
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| Samenvatting: | The role of the L-δ-(α-aminoadipoyl)-L-cysteinyl amide bond in isopenicillin N synthase catalysis is probed by the synthesis of two analogues of its tripeptide substrate L-δ-α-aminoadipoyl-L-cysteinyl-D-valine. |
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