Studies on side chain interactions during the isopenicillin N synthase catalysed biosynthesis of penicillins
The role of the L-δ-(α-aminoadipoyl)-L-cysteinyl amide bond in isopenicillin N synthase catalysis is probed by the synthesis of two analogues of its tripeptide substrate L-δ-α-aminoadipoyl-L-cysteinyl-D-valine.
Huvudupphovsmän: | , , , |
---|---|
Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
1997
|
Sammanfattning: | The role of the L-δ-(α-aminoadipoyl)-L-cysteinyl amide bond in isopenicillin N synthase catalysis is probed by the synthesis of two analogues of its tripeptide substrate L-δ-α-aminoadipoyl-L-cysteinyl-D-valine. |
---|