Studies on side chain interactions during the isopenicillin N synthase catalysed biosynthesis of penicillins

The role of the L-δ-(α-aminoadipoyl)-L-cysteinyl amide bond in isopenicillin N synthase catalysis is probed by the synthesis of two analogues of its tripeptide substrate L-δ-α-aminoadipoyl-L-cysteinyl-D-valine.

Bibliografiska uppgifter
Huvudupphovsmän: Cavelier, F, Russell, A, Schofield, C, Baldwin, J
Materialtyp: Journal article
Språk:English
Publicerad: 1997
Beskrivning
Sammanfattning:The role of the L-δ-(α-aminoadipoyl)-L-cysteinyl amide bond in isopenicillin N synthase catalysis is probed by the synthesis of two analogues of its tripeptide substrate L-δ-α-aminoadipoyl-L-cysteinyl-D-valine.