Studies on side chain interactions during the isopenicillin N synthase catalysed biosynthesis of penicillins
The role of the L-δ-(α-aminoadipoyl)-L-cysteinyl amide bond in isopenicillin N synthase catalysis is probed by the synthesis of two analogues of its tripeptide substrate L-δ-α-aminoadipoyl-L-cysteinyl-D-valine.
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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1997
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| _version_ | 1826270371669606400 |
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| author | Cavelier, F Russell, A Schofield, C Baldwin, J |
| author_facet | Cavelier, F Russell, A Schofield, C Baldwin, J |
| author_sort | Cavelier, F |
| collection | OXFORD |
| description | The role of the L-δ-(α-aminoadipoyl)-L-cysteinyl amide bond in isopenicillin N synthase catalysis is probed by the synthesis of two analogues of its tripeptide substrate L-δ-α-aminoadipoyl-L-cysteinyl-D-valine. |
| first_indexed | 2024-03-06T21:39:47Z |
| format | Journal article |
| id | oxford-uuid:47833128-2ba4-43fe-94e4-55aaa2ee6060 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:39:47Z |
| publishDate | 1997 |
| record_format | dspace |
| spelling | oxford-uuid:47833128-2ba4-43fe-94e4-55aaa2ee60602022-03-26T15:20:33ZStudies on side chain interactions during the isopenicillin N synthase catalysed biosynthesis of penicillinsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:47833128-2ba4-43fe-94e4-55aaa2ee6060EnglishSymplectic Elements at Oxford1997Cavelier, FRussell, ASchofield, CBaldwin, JThe role of the L-δ-(α-aminoadipoyl)-L-cysteinyl amide bond in isopenicillin N synthase catalysis is probed by the synthesis of two analogues of its tripeptide substrate L-δ-α-aminoadipoyl-L-cysteinyl-D-valine. |
| spellingShingle | Cavelier, F Russell, A Schofield, C Baldwin, J Studies on side chain interactions during the isopenicillin N synthase catalysed biosynthesis of penicillins |
| title | Studies on side chain interactions during the isopenicillin N synthase catalysed biosynthesis of penicillins |
| title_full | Studies on side chain interactions during the isopenicillin N synthase catalysed biosynthesis of penicillins |
| title_fullStr | Studies on side chain interactions during the isopenicillin N synthase catalysed biosynthesis of penicillins |
| title_full_unstemmed | Studies on side chain interactions during the isopenicillin N synthase catalysed biosynthesis of penicillins |
| title_short | Studies on side chain interactions during the isopenicillin N synthase catalysed biosynthesis of penicillins |
| title_sort | studies on side chain interactions during the isopenicillin n synthase catalysed biosynthesis of penicillins |
| work_keys_str_mv | AT cavelierf studiesonsidechaininteractionsduringtheisopenicillinnsynthasecatalysedbiosynthesisofpenicillins AT russella studiesonsidechaininteractionsduringtheisopenicillinnsynthasecatalysedbiosynthesisofpenicillins AT schofieldc studiesonsidechaininteractionsduringtheisopenicillinnsynthasecatalysedbiosynthesisofpenicillins AT baldwinj studiesonsidechaininteractionsduringtheisopenicillinnsynthasecatalysedbiosynthesisofpenicillins |