Characterization of O-antigen delivered by generalized modules for membrane antigens (GMMA) vaccine candidates against nontyphoidal Salmonella

Characterization of O-antigen delivered by generalized modules for membrane antigens (GMMA) vaccine candidates against nontyphoidal Salmonella

Invasive nontyphoidal Salmonella disease (iNTS) is a leading cause of death and morbidity in Africa. The most common pathogens are Salmonella enterica serovars Typhimurium and Enteritidis. The O-antigen portion of their lipopolysaccharide is a target of protective immunity and vaccines targeting O-a...

Полное описание

Библиографические подробности
Главные авторы:	De Benedetto, G, Alfini, R, Cescutti, P, Caboni, M, Lanzilao, L, Necchi, F, Saul, A, MacLennan, C, Rondini, S, Micoli, F
Формат:	Journal article
Язык:	English
Опубликовано:	Elsevier 2016

Схожие документы

Strain selection for generation of O-antigen-based glycoconjugate vaccines against invasive nontyphoidal salmonella disease
по: Lanzilao, L, и др.
Опубликовано: (2015)

Strain Selection for Generation of O-Antigen-Based Glycoconjugate Vaccines against Invasive Nontyphoidal Salmonella Disease.
по: Luisa Lanzilao, и др.
Опубликовано: (2015-01-01)

Relationship between antibody susceptibility and lipopolysaccharide O-antigen characteristics of invasive and gastrointestinal nontyphoidal Salmonellae isolates from Kenya.
по: Robert S Onsare, и др.
Опубликовано: (2015-03-01)

Toll-like receptor activation by generalized modules for membrane antigens from lipid a mutants of salmonella enterica serovars typhimurium and enteritidis
по: Rossi, O, и др.
Опубликовано: (2016)

Comparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate vaccines against nontyphoidal Salmonella
по: Micoli, F, и др.
Опубликовано: (2018)

Dissecting the contribution of O-Antigen and proteins to the immunogenicity of Shigella sonnei generalized modules for membrane antigens (GMMA)
по: Francesca Mancini, и др.
Опубликовано: (2021-01-01)

Immunogenicity of a bivalent adjuvanted glycoconjugate vaccine against salmonella typhimurium and salmonella enteritidis.
по: Fiorino, F, и др.
Опубликовано: (2017)

Rapid generation of Shigella flexneri GMMA displaying natural or new and cross-reactive O-Antigens
по: Gianmarco Gasperini, и др.
Опубликовано: (2022-06-01)

The background, role and approach for development of a controlled human infection model for nontyphoidal Salmonella
по: MacLennan, CA
Опубликовано: (2021)

Cross-sectional study of IgG antibody levels to invasive nontyphoidal Salmonella LPS O-antigen with age in Uganda
по: Stockdale, L, и др.
Опубликовано: (2019)

GMMA Is a Versatile Platform to Design Effective Multivalent Combination Vaccines
по: Francesca Micoli, и др.
Опубликовано: (2020-09-01)

Nontyphoidal salmonella disease: Current status of vaccine research and development.
по: Tennant, S, и др.
Опубликовано: (2016)

<i>Neisseria meningitidis</i> Factor H Binding Protein Surface Exposure on <i>Salmonella</i> Typhimurium GMMA Is Critical to Induce an Effective Immune Response against Both Diseases
по: Francesca Necchi, и др.
Опубликовано: (2021-06-01)

GMMA-Based Vaccines: The Known and The Unknown
по: Francesca Mancini, и др.
Опубликовано: (2021-08-01)

Multiple Techniques for Size Determination of Generalized Modules for Membrane Antigens from Salmonella typhimurium and Salmonella enteritidis
по: Gianluigi De Benedetto, и др.
Опубликовано: (2017-11-01)

Investigating the Role of Antigen Orientation on the Immune Response Elicited by <i>Neisseria meningitidis</i> Factor H Binding Protein on GMMA
по: Renzo Alfini, и др.
Опубликовано: (2022-07-01)

A next-generation GMMA-based vaccine candidate to fight shigellosis
по: Omar Rossi, и др.
Опубликовано: (2023-09-01)

GMMA and Glycoconjugate Approaches Compared in Mice for the Development of a Vaccine against <i>Shigella flexneri</i> Serotype 6
по: Maria Michelina Raso, и др.
Опубликовано: (2020-04-01)

A systematic review of the incidence, risk factors and case fatality rates of invasive Nontyphoidal Salmonella (iNTS) Disease in Africa (1966 to 2014)
по: Uche, I, и др.
Опубликовано: (2017)

Invasive nontyphoidal salmonella disease in Africa
по: Gilchrist, J, и др.
Опубликовано: (2019)

Generalized Modules for Membrane Antigens (GMMA), an outer membrane vesicle‐based vaccine platform, for efficient viral antigen delivery
по: Kai Hu, и др.
Опубликовано: (2022-11-01)

Enhanced Systemic Humoral Immune Response Induced in Mice by Generalized Modules for Membrane Antigens (GMMA) Is Associated with Affinity Maturation and Isotype Switching
по: Diego Piccioli, и др.
Опубликовано: (2023-07-01)

A Systematic Review of the Incidence, Risk Factors and Case Fatality Rates of Invasive Nontyphoidal Salmonella (iNTS) Disease in Africa (1966 to 2014).
по: Ifeanyi Valentine Uche, и др.
Опубликовано: (2017-01-01)

Cytokine profiles during invasive nontyphoidal Salmonella disease predict outcome in African children.
по: Gilchrist, J, и др.
Опубликовано: (2016)

Cytokine profiles during invasive nontyphoidal Salmonella disease predict outcome in African children.
по: Gilchrist, J, и др.
Опубликовано: (2016)

Cross-sectional study of IgG antibody levels to invasive nontyphoidal Salmonella LPS O-antigen with age in Uganda [version 1; peer review: 2 approved]
по: Lisa Stockdale, и др.
Опубликовано: (2019-06-01)

Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4
по: Gilchrist, JJ, и др.
Опубликовано: (2018)

The influence of conjugation variables on the design and immunogenicity of a glycoconjugate vaccine against Salmonella Typhi.
по: Arcuri, M, и др.
Опубликовано: (2017)

Presentation of life-threatening invasive nontyphoidal Salmonella disease in Malawian children: A prospective observational study
по: MacLennan, C, и др.
Опубликовано: (2017)

Comparison of Shigella GMMA and glycoconjugate four-component formulations in animals
по: Roberta Di Benedetto, и др.
Опубликовано: (2023-11-01)

Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4
по: James J. Gilchrist, и др.
Опубликовано: (2018-03-01)

The influence of conjugation variables on the design and immunogenicity of a glycoconjugate vaccine against Salmonella Typhi.
по: M Arcuri, и др.
Опубликовано: (2017-01-01)

Sugar-protein connectivity impacts on the immunogenicity of site-selective salmonella O-antigen glycoconjugate vaccines
по: Stefanetti, G, и др.
Опубликовано: (2010)

Complementary measurement of nontyphoidal Salmonella-specific IgG and IgA antibodies in oral fluid and serum
по: Sean C. Elias, и др.
Опубликовано: (2023-01-01)

Production of a Shigella sonnei Vaccine Based on Generalized Modules for Membrane Antigens (GMMA), 1790GAHB.
по: Christiane Gerke, и др.
Опубликовано: (2015-01-01)

Early interferon-γ production in human lymphocyte subsets in response to nontyphoidal Salmonella demonstrates inherent capacity in innate cells.
по: Tonney S Nyirenda, и др.
Опубликовано: (2010-10-01)

Presentation of life-threatening invasive nontyphoidal Salmonella disease in Malawian children: A prospective observational study.
по: Calman A MacLennan, и др.
Опубликовано: (2017-12-01)

Differential killing of Salmonella enterica serovar Typhi by antibodies targeting Vi and lipopolysaccharide O:9 antigen
по: Hart, P, и др.
Опубликовано: (2016)

O:2-CRM(197) conjugates against Salmonella Paratyphi A.
по: Francesca Micoli, и др.
Опубликовано: (2012-01-01)

IgG responses to porins and lipopolysaccharide within an outer membrane-based vaccine against nontyphoidal salmonella develop at discordant rates
по: Schager, A, и др.
Опубликовано: (2018)