Common variations in the ALMS1 gene do not contribute to susceptibility to type 2 diabetes in a large white UK population.

Common variations in the ALMS1 gene do not contribute to susceptibility to type 2 diabetes in a large white UK population.

AIMS/HYPOTHESIS: Alström syndrome is a rare monogenic disorder characterised by retinal dystrophy, deafness and obesity. Patients also have insulin resistance, central obesity and dyslipidaemia, thus showing similarities with type 2 diabetes. Rare mutations in the ALMS1 gene cause severe gene disrup...

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Bibliographic Details
Main Authors:	Patel, S, Minton, J, Weedon, M, Frayling, T, Ricketts, C, Hitman, G, McCarthy, M, Hattersley, A, Walker, M, Barrett, T
Format:	Journal article
Language:	English
Published:	2006

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