What are we measuring with GABA magnetic resonance spectroscopy?
A number of recent papers1-3 have demonstrated a relationship between in vivo concentration of GABA, as assessed using Magnetic Resonance Spectroscopy (MRS), and an individual's task performance, giving a unique insight into the relationship between physiology and behavior. However, interpretat...
| Main Authors: | , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2011
|
| _version_ | 1826270404403003392 |
|---|---|
| author | Stagg, C Bachtiar, V Johansen-Berg, H |
| author_facet | Stagg, C Bachtiar, V Johansen-Berg, H |
| author_sort | Stagg, C |
| collection | OXFORD |
| description | A number of recent papers1-3 have demonstrated a relationship between in vivo concentration of GABA, as assessed using Magnetic Resonance Spectroscopy (MRS), and an individual's task performance, giving a unique insight into the relationship between physiology and behavior. However, interpretation of the functional significance of the MRS GABA measure is not straightforward. Here we discuss some of the outstanding questions as to how total concentration of GABA within a cortical region relates to phasic and tonic GABA activity within the cortical volume studied. |
| first_indexed | 2024-03-06T21:40:18Z |
| format | Journal article |
| id | oxford-uuid:47b4704a-01ad-4b2a-9e9e-8d23608896f1 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:40:18Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | oxford-uuid:47b4704a-01ad-4b2a-9e9e-8d23608896f12022-03-26T15:21:27ZWhat are we measuring with GABA magnetic resonance spectroscopy?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:47b4704a-01ad-4b2a-9e9e-8d23608896f1EnglishSymplectic Elements at Oxford2011Stagg, CBachtiar, VJohansen-Berg, HA number of recent papers1-3 have demonstrated a relationship between in vivo concentration of GABA, as assessed using Magnetic Resonance Spectroscopy (MRS), and an individual's task performance, giving a unique insight into the relationship between physiology and behavior. However, interpretation of the functional significance of the MRS GABA measure is not straightforward. Here we discuss some of the outstanding questions as to how total concentration of GABA within a cortical region relates to phasic and tonic GABA activity within the cortical volume studied. |
| spellingShingle | Stagg, C Bachtiar, V Johansen-Berg, H What are we measuring with GABA magnetic resonance spectroscopy? |
| title | What are we measuring with GABA magnetic resonance spectroscopy? |
| title_full | What are we measuring with GABA magnetic resonance spectroscopy? |
| title_fullStr | What are we measuring with GABA magnetic resonance spectroscopy? |
| title_full_unstemmed | What are we measuring with GABA magnetic resonance spectroscopy? |
| title_short | What are we measuring with GABA magnetic resonance spectroscopy? |
| title_sort | what are we measuring with gaba magnetic resonance spectroscopy |
| work_keys_str_mv | AT staggc whatarewemeasuringwithgabamagneticresonancespectroscopy AT bachtiarv whatarewemeasuringwithgabamagneticresonancespectroscopy AT johansenbergh whatarewemeasuringwithgabamagneticresonancespectroscopy |