The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells.

BACKGROUND: Less than 50% of ovarian cancers respond to paclitaxel. Effective strategies are needed to enhance paclitaxel sensitivity. METHODS: A library of silencing RNAs (siRNAs) was used to identify kinases that regulate paclitaxel sensitivity in human ovarian cancer SKOv3 cells. The effect of da...

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Detalhes bibliográficos
Main Authors: Le, X, Mao, W, He, G, Claret, F, Xia, W, Ahmed, A, Hung, M, Siddik, Z, Bast, R
Formato: Journal article
Idioma:English
Publicado em: 2011