The dyslexia-associated protein KIAA0319 interacts with adaptor protein 2 and follows the classical clathrin-mediated endocytosis pathway.

The dyslexia-associated protein KIAA0319 interacts with adaptor protein 2 and follows the classical clathrin-mediated endocytosis pathway.

Recently, genetic studies have implicated KIAA0319 in developmental dyslexia, the most common of the childhood learning disorders. The first functional data indicated that the KIAA0319 protein is expressed on the plasma membrane and may be involved in neuronal migration. Further analysis of the subc...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Levecque, C, Velayos-Baeza, A, Holloway, Z, Monaco, A
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2009

Παρόμοια τεκμήρια

The dyslexia-associated KIAA0319 protein undergoes proteolytic processing with {gamma}-secretase-independent intramembrane cleavage.
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Έκδοση: (2010)

Alternative splicing in the dyslexia-associated gene KIAA0319.
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Expression of the KIAA0319 gene from a haplotype associated with developmental dyslexia
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Έκδοση: (2006)

Knockout mice for dyslexia susceptibility gene homologs KIAA0319 and KIAA0319L have unaffected neuronal migration but display abnormal auditory processing
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Έκδοση: (2017)

The Dyslexia-susceptibility protein KIAA0319 inhibits axon growth through Smad2 signaling.
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Έκδοση: (2017)

Functional characterisation of dyslexia-susceptibility candidate genes KIAA0319 and KIAA0319L
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Έκδοση: (2017)

The dyslexia-associated gene KIAA0319 encodes highly N- and O-glycosylated plasma membrane and secreted isoforms.
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Έκδοση: (2008)

Normal radial migration and lamination are maintained in dyslexia-susceptibility candidate gene homolog Kiaa0319 knockout mice.
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Έκδοση: (2016)

Further evidence that KIAA0319 is associated with developmental dyslexia
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Έκδοση: (2006)

Further evidence that the KIAA0319 gene confers susceptibility to developmental dyslexia.
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Έκδοση: (2006)

Association of the KIAA0319 dyslexia susceptibility gene with reading skills in the general population.
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Έκδοση: (2008)

A common variant associated with dyslexia reduces expression of the KIAA0319 gene.
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Έκδοση: (2009)

A common variant associated with dyslexia reduces expression of the KIAA0319 gene.
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Έκδοση: (2009-03-01)

Linkage disequilibrium structure of KIAA0319 and DCDC2, two candidate susceptibility genes for developmental dyslexia
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Dyslexia associated gene KIAA0319 regulates cell cycle during human neuroepithelial cell development
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Έκδοση: (2022-08-01)

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Έκδοση: (2011)

DCDC2, KIAA0319 and CMIP are associated with reading-related traits.
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Έκδοση: (2011)

The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration.
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Έκδοση: (2006)

The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration
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Έκδοση: (2006)

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Έκδοση: (2010-03-01)

FACI is a novel clathrin adaptor protein 2-binding protein that facilitates low-density lipoprotein endocytosis
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Έκδοση: (2023-04-01)

Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis
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Έκδοση: (2018-03-01)

KIAA0319 influences cilia length, cell migration and mechanical cell–substrate interaction
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Έκδοση: (2022-01-01)

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Έκδοση: (2022-09-01)

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Έκδοση: (2021-05-01)

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Έκδοση: (2022-01-01)

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Clathrin mediated endocytosis - Methods and Protocols
ανά: Manuela Monti
Έκδοση: (2019-09-01)

Large self-assembled clathrin lattices spontaneously disassemble without sufficient adaptor proteins.
ανά: Si-Kao Guo, κ.ά.
Έκδοση: (2022-03-01)

Single-molecule turnover dynamics of actin and membrane coat proteins in clathrin-mediated endocytosis
ανά: Michael M Lacy, κ.ά.
Έκδοση: (2019-12-01)

Integrating protein copy numbers with interaction networks to quantify stoichiometry in clathrin-mediated endocytosis
ανά: Daisy Duan, κ.ά.
Έκδοση: (2022-03-01)

The membrane-associated proteins FCHo and SGIP are allosteric activators of the AP2 clathrin adaptor complex
ανά: Gunther Hollopeter, κ.ά.
Έκδοση: (2014-10-01)

Weak Molecular Interactions in Clathrin-Mediated Endocytosis
ανά: Sarah M. Smith, κ.ά.
Έκδοση: (2017-11-01)

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ανά: Emmanuel Boucrot, κ.ά.
Έκδοση: (2010-05-01)