The dyslexia-associated protein KIAA0319 interacts with adaptor protein 2 and follows the classical clathrin-mediated endocytosis pathway.
Recently, genetic studies have implicated KIAA0319 in developmental dyslexia, the most common of the childhood learning disorders. The first functional data indicated that the KIAA0319 protein is expressed on the plasma membrane and may be involved in neuronal migration. Further analysis of the subc...
Հիմնական հեղինակներ: | Levecque, C, Velayos-Baeza, A, Holloway, Z, Monaco, A |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2009
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Նմանատիպ նյութեր
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The dyslexia-associated KIAA0319 protein undergoes proteolytic processing with {gamma}-secretase-independent intramembrane cleavage.
: Velayos-Baeza, A, և այլն
Հրապարակվել է: (2010) -
Alternative splicing in the dyslexia-associated gene KIAA0319.
: Velayos-Baeza, A, և այլն
Հրապարակվել է: (2007) -
Expression of the KIAA0319 gene from a haplotype associated with developmental dyslexia
: Dennis, M, և այլն
Հրապարակվել է: (2006) -
Knockout mice for dyslexia susceptibility gene homologs KIAA0319 and
KIAA0319L have unaffected neuronal migration but display abnormal
auditory processing
: Guidi, L, և այլն
Հրապարակվել է: (2017) -
The Dyslexia-susceptibility protein KIAA0319 inhibits axon growth through Smad2 signaling.
: Franquinho, F, և այլն
Հրապարակվել է: (2017)