How does hypoxia-inducible factor (HIF) regulate osteoclastogenesis and bone erosion?

Eitemau Tebyg

• Hypoxia-Inducible Factor 1-alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl-4-hydroxylase 2
  gan: Hulley, P, et al.
  Cyhoeddwyd: (2017)
• Hypoxia, hypoxia-inducible factor (HIF) and bone homeostasis: focus on osteoclast-mediated bone resorption
  gan: Knowles, H
  Cyhoeddwyd: (2015)
• Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing.
  gan: Webb, J, et al.
  Cyhoeddwyd: (2009)
• Regulation of angiogenesis by hypoxia: role of the HIF system.
  gan: Pugh, C, et al.
  Cyhoeddwyd: (2003)
• Distinct roles for the hypoxia-inducible transcription factors HIF-1alpha and HIF-2alpha in human osteoclast formation and function
  gan: Knowles, H
  Cyhoeddwyd: (2020)