Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with severe influenza in Chinese individuals.

Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with severe influenza in Chinese individuals.

The SNP rs12252-C allele alters the function of interferon-induced transmembrane protein-3 increasing the disease severity of influenza virus infection in Caucasians, but the allele is rare. However, rs12252-C is much more common in Han Chinese. Here we report that the CC genotype is found in 69% of...

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Bibliographic Details
Main Authors: Zhang, Y, Zhao, Y, Li, N, Peng, Y, Giannoulatou, E, Jin, R, Yan, H, Wu, H, Liu, J, Liu, N, Wang, D, Shu, Y, Ho, L, Kellam, P, McMichael, A, Dong, T
Format: Journal article
Language:English
Published: Springer Nature 2013

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