Quinine in severe falciparum malaria: evidence of declining efficacy in Thailand.
Between 1981 and 1992, 196 Thai adults with severe falciparum malaria were treated with a quinine loading dose regimen. Nineteen patients died (10%) and 6 developed late hypoglycaemia. There was no serious cardiovascular or nervous system toxicity. Although there was no evidence of high grade resist...
Main Authors: | Pukrittayakamee, S, Supanaranond, W, Looareesuwan, S, Vanijanonta, S, White, N |
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Format: | Journal article |
Language: | English |
Published: |
1994
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