Molecular therapeutics of pancreatic ductal adenocarcinoma:targeted pathways and the role of cancer stem cells

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers in humans due to late detection and highly metastatic characteristics. PDAC cells vary in their tumorigenic capabilities with the presence of a subset of PDAC cells known as pancreatic cancer stem cells (CSCs), which are more...

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Bibliographic Details
Main Authors: Stoica, A, Chang, C-H, Pauklin, S
Format: Journal article
Language:English
Published: Cell Press 2020