Long-acting inhaled anticholinergic therapy improves sleeping oxygen saturation in COPD.

Oxygen desaturation occurs during sleep in severe chronic obstructive pulmonary disease (COPD), especially during rapid eye movement (REM) sleep, due to hypoventilation and ventilation-perfusion mismatching, but the possible contribution of airflow limitation is unclear. In a randomised, placebo-con...

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Main Authors: McNicholas, W, Calverley, P, Lee, A, Edwards, J
格式: Journal article
语言:English
出版: 2004