Kinetic landscape of a peptide bond-forming prolyl oligopeptidase
Prolyl oligopeptidase B from Galerina marginata (GmPOPB) has recently been discovered as a peptidase capable of breaking and forming peptide bonds to yield a cyclic peptide. Despite the relevance of prolyl oligopeptidases in human biology and disease, a kinetic analysis pinpointing rate-limiting ste...
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Médium: | Journal article |
Jazyk: | English |
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American Chemical Society
2017
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