Kinetic landscape of a peptide bond-forming prolyl oligopeptidase

Prolyl oligopeptidase B from Galerina marginata (GmPOPB) has recently been discovered as a peptidase capable of breaking and forming peptide bonds to yield a cyclic peptide. Despite the relevance of prolyl oligopeptidases in human biology and disease, a kinetic analysis pinpointing rate-limiting ste...

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Hlavní autoři: Czekster, C, Naismith, J
Médium: Journal article
Jazyk:English
Vydáno: American Chemical Society 2017