Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation.
OBJECTIVE: Colorectal cancer (CRC) is a major contributor to cancer mortality and morbidity. LIM kinase 2 (LIMK2) promotes tumour cell invasion and metastasis. The objectives of this study were to determine how LIMK2 expression is associated with CRC progression and patient outcome, and to use genet...
المؤلفون الرئيسيون: | Lourenço, F, Munro, J, Brown, J, Cordero, J, Stefanatos, R, Strathdee, K, Orange, C, Feller, S, Sansom, O, Vidal, M, Murray, G, Olson, M |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2014
|
مواد مشابهة
-
LIMK1 and LIMK2 regulate cortical development through affecting neural progenitor cell proliferation and migration
حسب: Rui Mao, وآخرون
منشور في: (2019-07-01) -
Keratinocyte migration in the developing eyelid requires LIMK2.
حسب: Dennis S Rice, وآخرون
منشور في: (2012-01-01) -
Structural Aspects of LIMK Regulation and Pharmacology
حسب: Deep Chatterjee, وآخرون
منشور في: (2022-01-01) -
LIM Kinases, LIMK1 and LIMK2, Are Crucial Node Actors of the Cell Fate: Molecular to Pathological Features
حسب: Elodie Villalonga, وآخرون
منشور في: (2023-03-01) -
MiR-106a directly targets LIMK1 to inhibit proliferation and EMT of oral carcinoma cells
حسب: Bingxia Shi, وآخرون
منشور في: (2019-03-01)