Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation.

Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation.

OBJECTIVE: Colorectal cancer (CRC) is a major contributor to cancer mortality and morbidity. LIM kinase 2 (LIMK2) promotes tumour cell invasion and metastasis. The objectives of this study were to determine how LIMK2 expression is associated with CRC progression and patient outcome, and to use genet...

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Hlavní autoři: Lourenço, F, Munro, J, Brown, J, Cordero, J, Stefanatos, R, Strathdee, K, Orange, C, Feller, S, Sansom, O, Vidal, M, Murray, G, Olson, M
Médium: Journal article
Jazyk:English
Vydáno: 2014

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