Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation.
OBJECTIVE: Colorectal cancer (CRC) is a major contributor to cancer mortality and morbidity. LIM kinase 2 (LIMK2) promotes tumour cell invasion and metastasis. The objectives of this study were to determine how LIMK2 expression is associated with CRC progression and patient outcome, and to use genet...
Үндсэн зохиолчид: | Lourenço, F, Munro, J, Brown, J, Cordero, J, Stefanatos, R, Strathdee, K, Orange, C, Feller, S, Sansom, O, Vidal, M, Murray, G, Olson, M |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
2014
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