Targeting endothelial cells with adenovirus expressing nitric oxide synthase prevents elevation of blood pressure in stroke-prone spontaneously hypertensive rats.

Targeting endothelial cells with adenovirus expressing nitric oxide synthase prevents elevation of blood pressure in stroke-prone spontaneously hypertensive rats.

Local adenoviral (Ad)-mediated gene transfer to the carotid artery of the stroke-prone spontaneously hypertensive rat (SHRSP) is successful in improving endothelial function. Here we explored the potential of systemic delivery of Ad encoding endothelial nitric oxide synthase (AdeNOS) to prevent elev...

書誌詳細
主要な著者:	Miller, W, Brosnan, M, Graham, D, Nicol, C, Morecroft, I, Channon, K, Danilov, S, Reynolds, P, Baker, A, Dominiczak, A
フォーマット:	Journal article
言語:	English
出版事項:	2005

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