Population pharmacokinetics of mefloquine in patients with acute falciparum malaria.

OBJECTIVE: To construct a population pharmacokinetic model for mefloquine in the treatment of falciparum malaria. BACKGROUND: Mefloquine is the treatment of choice for multidrug-resistant falciparum malaria. The factors that influence the pharmacokinetic properties of mefloquine in acute malaria are...

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Bibliografiske detaljer
Main Authors: Simpson, J, Price, R, ter Kuile, F, Teja-Isavatharm, P, Nosten, F, Chongsuphajaisiddhi, T, Looareesuwan, S, Aarons, L, White, N
Format: Journal article
Sprog:English
Udgivet: 1999