Disc size markedly influences concentration profiles of intravenously administered solutes in the intervertebral disc: a computational study on glucosamine as a model solute
Purpose: Tests on animals of different species with large differences in intervertebral disc size are commonly used to investigate the therapeutic efficacy of intravenously injected solutes in the disc. We hypothesize that disc size markedly affects outcome. Methods: Here, using a small non-metaboli...
Үндсэн зохиолчид: | Motaghinasab, S, Parnianpour, M, Shirazi-Adl, A, Urban, J |
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Формат: | Journal article |
Хэвлэсэн: |
2013
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Ижил төстэй зүйлс
Ижил төстэй зүйлс
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Disc size markedly influences concentration profiles of intravenously administered solutes in the intervertebral disc: A computational study on glucosamine as a model solute
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Computational pharmacokinetics of solute penetration into human intervertebral discs - effects of endplate permeability, solute molecular weight and disc size.
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