Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage.

We present a two-stage genomewide scan for osteoarthritis-susceptibility loci, using 481 families that each contain at least one affected sibling pair. The first stage, with 272 microsatellite markers and 297 families, involved a sparse map covering 23 chromosomes at intervals of approximately 15 cM...

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Main Authors: Chapman, K, Mustafa, Z, Irven, C, Carr, A, Clipsham, K, Smith, A, Chitnavis, J, Sinsheimer, J, Bloomfield, V, McCartney, M, Cox, O, Cardon, L, Sykes, B, Loughlin, J
Format: Journal article
Language:English
Published: 1999
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author Chapman, K
Mustafa, Z
Irven, C
Carr, A
Clipsham, K
Smith, A
Chitnavis, J
Sinsheimer, J
Bloomfield, V
McCartney, M
Cox, O
Cardon, L
Sykes, B
Loughlin, J
author_facet Chapman, K
Mustafa, Z
Irven, C
Carr, A
Clipsham, K
Smith, A
Chitnavis, J
Sinsheimer, J
Bloomfield, V
McCartney, M
Cox, O
Cardon, L
Sykes, B
Loughlin, J
author_sort Chapman, K
collection OXFORD
description We present a two-stage genomewide scan for osteoarthritis-susceptibility loci, using 481 families that each contain at least one affected sibling pair. The first stage, with 272 microsatellite markers and 297 families, involved a sparse map covering 23 chromosomes at intervals of approximately 15 cM. Sixteen markers that showed evidence of linkage at nominal P
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spelling oxford-uuid:486fc3c1-2ad4-47f6-81f6-119679f7c5ed2022-03-26T15:25:48ZOsteoarthritis-susceptibility locus on chromosome 11q, detected by linkage.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:486fc3c1-2ad4-47f6-81f6-119679f7c5edEnglishSymplectic Elements at Oxford1999Chapman, KMustafa, ZIrven, CCarr, AClipsham, KSmith, AChitnavis, JSinsheimer, JBloomfield, VMcCartney, MCox, OCardon, LSykes, BLoughlin, JWe present a two-stage genomewide scan for osteoarthritis-susceptibility loci, using 481 families that each contain at least one affected sibling pair. The first stage, with 272 microsatellite markers and 297 families, involved a sparse map covering 23 chromosomes at intervals of approximately 15 cM. Sixteen markers that showed evidence of linkage at nominal P
spellingShingle Chapman, K
Mustafa, Z
Irven, C
Carr, A
Clipsham, K
Smith, A
Chitnavis, J
Sinsheimer, J
Bloomfield, V
McCartney, M
Cox, O
Cardon, L
Sykes, B
Loughlin, J
Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage.
title Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage.
title_full Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage.
title_fullStr Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage.
title_full_unstemmed Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage.
title_short Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage.
title_sort osteoarthritis susceptibility locus on chromosome 11q detected by linkage
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