Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage.
We present a two-stage genomewide scan for osteoarthritis-susceptibility loci, using 481 families that each contain at least one affected sibling pair. The first stage, with 272 microsatellite markers and 297 families, involved a sparse map covering 23 chromosomes at intervals of approximately 15 cM...
Main Authors: | , , , , , , , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1999
|
_version_ | 1826270550324936704 |
---|---|
author | Chapman, K Mustafa, Z Irven, C Carr, A Clipsham, K Smith, A Chitnavis, J Sinsheimer, J Bloomfield, V McCartney, M Cox, O Cardon, L Sykes, B Loughlin, J |
author_facet | Chapman, K Mustafa, Z Irven, C Carr, A Clipsham, K Smith, A Chitnavis, J Sinsheimer, J Bloomfield, V McCartney, M Cox, O Cardon, L Sykes, B Loughlin, J |
author_sort | Chapman, K |
collection | OXFORD |
description | We present a two-stage genomewide scan for osteoarthritis-susceptibility loci, using 481 families that each contain at least one affected sibling pair. The first stage, with 272 microsatellite markers and 297 families, involved a sparse map covering 23 chromosomes at intervals of approximately 15 cM. Sixteen markers that showed evidence of linkage at nominal P |
first_indexed | 2024-03-06T21:42:35Z |
format | Journal article |
id | oxford-uuid:486fc3c1-2ad4-47f6-81f6-119679f7c5ed |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T21:42:35Z |
publishDate | 1999 |
record_format | dspace |
spelling | oxford-uuid:486fc3c1-2ad4-47f6-81f6-119679f7c5ed2022-03-26T15:25:48ZOsteoarthritis-susceptibility locus on chromosome 11q, detected by linkage.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:486fc3c1-2ad4-47f6-81f6-119679f7c5edEnglishSymplectic Elements at Oxford1999Chapman, KMustafa, ZIrven, CCarr, AClipsham, KSmith, AChitnavis, JSinsheimer, JBloomfield, VMcCartney, MCox, OCardon, LSykes, BLoughlin, JWe present a two-stage genomewide scan for osteoarthritis-susceptibility loci, using 481 families that each contain at least one affected sibling pair. The first stage, with 272 microsatellite markers and 297 families, involved a sparse map covering 23 chromosomes at intervals of approximately 15 cM. Sixteen markers that showed evidence of linkage at nominal P |
spellingShingle | Chapman, K Mustafa, Z Irven, C Carr, A Clipsham, K Smith, A Chitnavis, J Sinsheimer, J Bloomfield, V McCartney, M Cox, O Cardon, L Sykes, B Loughlin, J Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage. |
title | Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage. |
title_full | Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage. |
title_fullStr | Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage. |
title_full_unstemmed | Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage. |
title_short | Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage. |
title_sort | osteoarthritis susceptibility locus on chromosome 11q detected by linkage |
work_keys_str_mv | AT chapmank osteoarthritissusceptibilitylocusonchromosome11qdetectedbylinkage AT mustafaz osteoarthritissusceptibilitylocusonchromosome11qdetectedbylinkage AT irvenc osteoarthritissusceptibilitylocusonchromosome11qdetectedbylinkage AT carra osteoarthritissusceptibilitylocusonchromosome11qdetectedbylinkage AT clipshamk osteoarthritissusceptibilitylocusonchromosome11qdetectedbylinkage AT smitha osteoarthritissusceptibilitylocusonchromosome11qdetectedbylinkage AT chitnavisj osteoarthritissusceptibilitylocusonchromosome11qdetectedbylinkage AT sinsheimerj osteoarthritissusceptibilitylocusonchromosome11qdetectedbylinkage AT bloomfieldv osteoarthritissusceptibilitylocusonchromosome11qdetectedbylinkage AT mccartneym osteoarthritissusceptibilitylocusonchromosome11qdetectedbylinkage AT coxo osteoarthritissusceptibilitylocusonchromosome11qdetectedbylinkage AT cardonl osteoarthritissusceptibilitylocusonchromosome11qdetectedbylinkage AT sykesb osteoarthritissusceptibilitylocusonchromosome11qdetectedbylinkage AT loughlinj osteoarthritissusceptibilitylocusonchromosome11qdetectedbylinkage |