Age-related macular degeneration: suitability of optogenetic therapy for geographic atrophy

Age-related macular degeneration: suitability of optogenetic therapy for geographic atrophy

Age-related macular degeneration (AMD) is a growing public health concern given the aging population and it is the leading cause of blindness in developed countries, affecting individuals over the age of 55 years. AMD affects the retinal pigment epithelium (RPE) and Bruch’s membrane in the macula, l...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Borchert, GA, Shamsnajafabadi, H, Ng, BWJ, Xue, K, De Silva, SR, Downes, SM, MacLaren, RE, Cehajic-Kapetanovic, J
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	Frontiers Media 2024

Eitemau Tebyg

Age-related macular degeneration: suitability of optogenetic therapy for geographic atrophy
gan: Grace A. Borchert, et al.
Cyhoeddwyd: (2024-07-01)

The Role of Inflammation in Age-Related Macular Degeneration—Therapeutic Landscapes in Geographic Atrophy
gan: Grace A. Borchert, et al.
Cyhoeddwyd: (2023-08-01)

Optogenetic Gene Therapy for the Degenerate Retina: Recent Advances
gan: Michelle E. McClements, et al.
Cyhoeddwyd: (2020-11-01)

Real-world six-month outcomes in patients switched to faricimab following partial response to anti-VEGF therapy for neovascular age-related macular degeneration and diabetic macular oedema
gan: Borchert, GA, et al.
Cyhoeddwyd: (2024)

Current and Future Landscape in Genetic Therapies for Leber Hereditary Optic Neuropathy
gan: Hoda Shamsnajafabadi, et al.
Cyhoeddwyd: (2023-08-01)

Gene therapy for age-related macular degeneration
gan: MacLaren, RE
Cyhoeddwyd: (2015)

Robotising vitreoretinal surgeries
gan: Mi, H, et al.
Cyhoeddwyd: (2024)

Geographic Atrophy in Age-Related Macular Degeneration
gan: Tiarnan D.L. Keenan, BM BCh, PhD
Cyhoeddwyd: (2023-09-01)

Genome-editing strategies for treating human retinal degenerations
gan: Quinn, J, et al.
Cyhoeddwyd: (2021)

A novel splice-site variant in CDH23 in a patient with Usher syndrome type 1
gan: Menghini, M, et al.
Cyhoeddwyd: (2019)

RPGR gene therapy presents challenges in cloning the coding sequence
gan: Martinez-Fernandez De La Camara, C, et al.
Cyhoeddwyd: (2019)

Local progression kinetics of geographic atrophy in age-related macular degeneration are associated with atrophy border morphology
gan: Lindner, M, et al.
Cyhoeddwyd: (2018)

Characterizing visual fields in RPGR related retinitis pigmentosa using octopus static-automated perimetry
gan: Buckley, TMW, et al.
Cyhoeddwyd: (2022)

Microperimetry hill of vision and volumetric measures of retinal sensitivity
gan: Josan, AS, et al.
Cyhoeddwyd: (2021)

Clinical applications of microperimetry in RPGR-related retinitis pigmentosa: a review
gan: Buckley, TMW, et al.
Cyhoeddwyd: (2021)

Prognostic value of shape-descriptive factors for the progression of geographic atrophy secondary to age-related macular degeneration
gan: Pfau, M, et al.
Cyhoeddwyd: (2019)

Levodopa is associated with reduced development of new-onset geographic atrophy in patients with age-related macular degeneration
gan: Kyle S. Chan, et al.
Cyhoeddwyd: (2024-11-01)

Light sensitivity within areas of geographic atrophy secondary to age-related macular degeneration
gan: Pfau, M, et al.
Cyhoeddwyd: (2019)

Population Pharmacokinetics of Pegcetacoplan in Patients with Geographic Atrophy or Neovascular Age-related Macular Degeneration
gan: Ryan L. Crass, PharmD, et al.
Cyhoeddwyd: (2025-03-01)

Advancements in Imaging and Therapeutic Options for Dry Age-Related Macular Degeneration and Geographic Atrophy
gan: Andrea Servillo, et al.
Cyhoeddwyd: (2024-06-01)

Emerging Treatment Options for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration
gan: Khan H, et al.
Cyhoeddwyd: (2023-01-01)

Choriocapillaris changes in dry age-related macular degeneration and geographic atrophy: a review
gan: Malvika Arya, et al.
Cyhoeddwyd: (2018-09-01)

Deep Learning Approaches for Detecting of Nascent Geographic Atrophy in Age-Related Macular Degeneration
gan: Heming Yao, PhD, et al.
Cyhoeddwyd: (2024-05-01)

Targeted High-Density Microperimetry Testing of Nascent Geographic Atrophy in Age-Related Macular Degeneration
gan: Zhichao Wu, BAppSc(Optom), PhD, et al.
Cyhoeddwyd: (2024-03-01)

Prevalence and Genetic Characteristics of Geographic Atrophy among Elderly Japanese with Age-Related Macular Degeneration.
gan: Yoichi Sakurada, et al.
Cyhoeddwyd: (2016-01-01)

Clinical and genetic factors associated with progression of geographic atrophy lesions in age-related macular degeneration.
gan: Felix Grassmann, et al.
Cyhoeddwyd: (2015-01-01)

Plasma biomarkers of the amyloid pathway are associated with geographic atrophy secondary to age-related macular degeneration.
gan: Kameran Lashkari, et al.
Cyhoeddwyd: (2020-01-01)

Association of a novel intronic variant in RPGR with hypomorphic phenotype of x-linked retinitis pigmentosa
gan: Cehajic-Kapetanovic, J, et al.
Cyhoeddwyd: (2020)

Current advances in multimodal imaging in geographic atrophy secondary to age-related macular degeneration: A review
gan: Amy C. Cohn, et al.
Cyhoeddwyd: (2024-12-01)

Automatic Quantification Software for Geographic Atrophy Associated with Age-Related Macular Degeneration: A Validation Study
gan: José M. Ruiz-Moreno, et al.
Cyhoeddwyd: (2020-01-01)

C1q and the classical complement cascade in geographic atrophy secondary to age-related macular degeneration
gan: Ted Yednock, et al.
Cyhoeddwyd: (2022-11-01)

Phase 1 Clinical Trial of Elamipretide in Dry Age-Related Macular Degeneration and Noncentral Geographic Atrophy
gan: Priyatham S. Mettu, MD, et al.
Cyhoeddwyd: (2022-03-01)

Local Complement Inhibition for Geographic Atrophy in Age-Related Macular Degeneration: Prospects, Challenges, and Unanswered Questions
gan: Tiarnan D.L. Keenan, BM BCh, PhD
Cyhoeddwyd: (2021-12-01)

Geographic atrophy in patients with advanced dry age-related macular degeneration: current challenges and future prospects
gan: Danis RP, et al.
Cyhoeddwyd: (2015-11-01)

CDHR1-related late-onset macular dystrophy: further insights
gan: Yusuf, IH, et al.
Cyhoeddwyd: (2020)

Gene-agnostic therapeutic approaches for inherited retinal degenerations
gan: Molly C. John, et al.
Cyhoeddwyd: (2023-01-01)

Rehabilitation Methods for Patients with Geographic Atrophy due to Age-Related Macular Degeneration and Effects of Rehabilitation on Quality of Life
gan: Damla Erginturk Acar, et al.
Cyhoeddwyd: (2023-01-01)

Circulating Anti-Endothelial Cell Antibodies in Patients with Geographic Atrophy Related to Dry Age-Related Macular Degeneration
gan: Katarzyna Żuber-Łaskawiec, et al.
Cyhoeddwyd: (2024-05-01)

Recent Advances in Imaging Macular Atrophy for Late-Stage Age-Related Macular Degeneration
gan: Anny M. S. Cheng, et al.
Cyhoeddwyd: (2023-12-01)

Dynamic in vivo quantification of rod photoreceptor degeneration using fluorescent reporter mouse models of retinitis pigmentosa
gan: Orlans, HO, et al.
Cyhoeddwyd: (2019)