Age-related macular degeneration: suitability of optogenetic therapy for geographic atrophy

Age-related macular degeneration: suitability of optogenetic therapy for geographic atrophy

Age-related macular degeneration (AMD) is a growing public health concern given the aging population and it is the leading cause of blindness in developed countries, affecting individuals over the age of 55 years. AMD affects the retinal pigment epithelium (RPE) and Bruch’s membrane in the macula, l...

Полное описание

Библиографические подробности
Главные авторы:	Borchert, GA, Shamsnajafabadi, H, Ng, BWJ, Xue, K, De Silva, SR, Downes, SM, MacLaren, RE, Cehajic-Kapetanovic, J
Формат:	Journal article
Язык:	English
Опубликовано:	Frontiers Media 2024

Схожие документы

Age-related macular degeneration: suitability of optogenetic therapy for geographic atrophy
по: Grace A. Borchert, и др.
Опубликовано: (2024-07-01)

The Role of Inflammation in Age-Related Macular Degeneration—Therapeutic Landscapes in Geographic Atrophy
по: Grace A. Borchert, и др.
Опубликовано: (2023-08-01)

Optogenetic Gene Therapy for the Degenerate Retina: Recent Advances
по: Michelle E. McClements, и др.
Опубликовано: (2020-11-01)

Real-world six-month outcomes in patients switched to faricimab following partial response to anti-VEGF therapy for neovascular age-related macular degeneration and diabetic macular oedema
по: Borchert, GA, и др.
Опубликовано: (2024)

Current and Future Landscape in Genetic Therapies for Leber Hereditary Optic Neuropathy
по: Hoda Shamsnajafabadi, и др.
Опубликовано: (2023-08-01)

Gene therapy for age-related macular degeneration
по: MacLaren, RE
Опубликовано: (2015)

Robotising vitreoretinal surgeries
по: Mi, H, и др.
Опубликовано: (2024)

Geographic Atrophy in Age-Related Macular Degeneration
по: Tiarnan D.L. Keenan, BM BCh, PhD
Опубликовано: (2023-09-01)

Genome-editing strategies for treating human retinal degenerations
по: Quinn, J, и др.
Опубликовано: (2021)

A novel splice-site variant in CDH23 in a patient with Usher syndrome type 1
по: Menghini, M, и др.
Опубликовано: (2019)

RPGR gene therapy presents challenges in cloning the coding sequence
по: Martinez-Fernandez De La Camara, C, и др.
Опубликовано: (2019)

Local progression kinetics of geographic atrophy in age-related macular degeneration are associated with atrophy border morphology
по: Lindner, M, и др.
Опубликовано: (2018)

Characterizing visual fields in RPGR related retinitis pigmentosa using octopus static-automated perimetry
по: Buckley, TMW, и др.
Опубликовано: (2022)

Microperimetry hill of vision and volumetric measures of retinal sensitivity
по: Josan, AS, и др.
Опубликовано: (2021)

Clinical applications of microperimetry in RPGR-related retinitis pigmentosa: a review
по: Buckley, TMW, и др.
Опубликовано: (2021)

Prognostic value of shape-descriptive factors for the progression of geographic atrophy secondary to age-related macular degeneration
по: Pfau, M, и др.
Опубликовано: (2019)

Levodopa is associated with reduced development of new-onset geographic atrophy in patients with age-related macular degeneration
по: Kyle S. Chan, и др.
Опубликовано: (2024-11-01)

Light sensitivity within areas of geographic atrophy secondary to age-related macular degeneration
по: Pfau, M, и др.
Опубликовано: (2019)

Population Pharmacokinetics of Pegcetacoplan in Patients with Geographic Atrophy or Neovascular Age-related Macular Degeneration
по: Ryan L. Crass, PharmD, и др.
Опубликовано: (2025-03-01)

Advancements in Imaging and Therapeutic Options for Dry Age-Related Macular Degeneration and Geographic Atrophy
по: Andrea Servillo, и др.
Опубликовано: (2024-06-01)

Emerging Treatment Options for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration
по: Khan H, и др.
Опубликовано: (2023-01-01)

Choriocapillaris changes in dry age-related macular degeneration and geographic atrophy: a review
по: Malvika Arya, и др.
Опубликовано: (2018-09-01)

Deep Learning Approaches for Detecting of Nascent Geographic Atrophy in Age-Related Macular Degeneration
по: Heming Yao, PhD, и др.
Опубликовано: (2024-05-01)

Targeted High-Density Microperimetry Testing of Nascent Geographic Atrophy in Age-Related Macular Degeneration
по: Zhichao Wu, BAppSc(Optom), PhD, и др.
Опубликовано: (2024-03-01)

Prevalence and Genetic Characteristics of Geographic Atrophy among Elderly Japanese with Age-Related Macular Degeneration.
по: Yoichi Sakurada, и др.
Опубликовано: (2016-01-01)

Clinical and genetic factors associated with progression of geographic atrophy lesions in age-related macular degeneration.
по: Felix Grassmann, и др.
Опубликовано: (2015-01-01)

Plasma biomarkers of the amyloid pathway are associated with geographic atrophy secondary to age-related macular degeneration.
по: Kameran Lashkari, и др.
Опубликовано: (2020-01-01)

Association of a novel intronic variant in RPGR with hypomorphic phenotype of x-linked retinitis pigmentosa
по: Cehajic-Kapetanovic, J, и др.
Опубликовано: (2020)

Current advances in multimodal imaging in geographic atrophy secondary to age-related macular degeneration: A review
по: Amy C. Cohn, и др.
Опубликовано: (2024-12-01)

Automatic Quantification Software for Geographic Atrophy Associated with Age-Related Macular Degeneration: A Validation Study
по: José M. Ruiz-Moreno, и др.
Опубликовано: (2020-01-01)

C1q and the classical complement cascade in geographic atrophy secondary to age-related macular degeneration
по: Ted Yednock, и др.
Опубликовано: (2022-11-01)

Phase 1 Clinical Trial of Elamipretide in Dry Age-Related Macular Degeneration and Noncentral Geographic Atrophy
по: Priyatham S. Mettu, MD, и др.
Опубликовано: (2022-03-01)

Local Complement Inhibition for Geographic Atrophy in Age-Related Macular Degeneration: Prospects, Challenges, and Unanswered Questions
по: Tiarnan D.L. Keenan, BM BCh, PhD
Опубликовано: (2021-12-01)

Geographic atrophy in patients with advanced dry age-related macular degeneration: current challenges and future prospects
по: Danis RP, и др.
Опубликовано: (2015-11-01)

CDHR1-related late-onset macular dystrophy: further insights
по: Yusuf, IH, и др.
Опубликовано: (2020)

Gene-agnostic therapeutic approaches for inherited retinal degenerations
по: Molly C. John, и др.
Опубликовано: (2023-01-01)

Rehabilitation Methods for Patients with Geographic Atrophy due to Age-Related Macular Degeneration and Effects of Rehabilitation on Quality of Life
по: Damla Erginturk Acar, и др.
Опубликовано: (2023-01-01)

Circulating Anti-Endothelial Cell Antibodies in Patients with Geographic Atrophy Related to Dry Age-Related Macular Degeneration
по: Katarzyna Żuber-Łaskawiec, и др.
Опубликовано: (2024-05-01)

Recent Advances in Imaging Macular Atrophy for Late-Stage Age-Related Macular Degeneration
по: Anny M. S. Cheng, и др.
Опубликовано: (2023-12-01)

Dynamic in vivo quantification of rod photoreceptor degeneration using fluorescent reporter mouse models of retinitis pigmentosa
по: Orlans, HO, и др.
Опубликовано: (2019)