HIV reverse transcriptase structures: designing new inhibitors and understanding mechanisms of drug resistance.
HIV reverse transcriptase (RT) is one of the main targets for the action of anti-AIDS drugs. The selection of drug-resistant HIV is a key problem in the continued treatment of the infection and thus new drugs are required. A significant body of information consisting of HIV-1 RT crystal structures w...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
2005
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