Alpha-1,2-mannosidase and hence N-glycosylation are required for regulatory T cell migration and allograft tolerance in mice.
BACKGROUND: Specific immunological unresponsiveness to alloantigens can be induced in vivo by treating mice with a donor alloantigen in combination with a non-depleting anti-CD4 antibody. This tolerance induction protocol enriches for alloantigen reactive regulatory T cells (Treg). We previously de...
Glavni autori: | Long, E, Baker, S, Oliveira, V, Sawitzki, B, Wood, K |
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Format: | Journal article |
Jezik: | English |
Izdano: |
Public Library of Science
2010
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Slični predmeti
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Alpha-1,2-mannosidase and hence N-glycosylation are required for regulatory T cell migration and allograft tolerance in mice.
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