Harnessing FOXP3+ regulatory T cells for transplantation tolerance.
Early demonstrations that mice could be tolerized to transplanted tissues with short courses of immunosuppressive therapy and that with regard to tolerance to self, CD4+FOXP3+ regulatory T cells (Tregs) appeared to play a critical role, have catalyzed strategies to harness FOXP3-dependent processes...
Hauptverfasser: | Waldmann, H, Hilbrands, R, Howie, D, Cobbold, S |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
American Society for Clinical Investigation
2014
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