Harnessing FOXP3+ regulatory T cells for transplantation tolerance.
Early demonstrations that mice could be tolerized to transplanted tissues with short courses of immunosuppressive therapy and that with regard to tolerance to self, CD4+FOXP3+ regulatory T cells (Tregs) appeared to play a critical role, have catalyzed strategies to harness FOXP3-dependent processes...
Principais autores: | , , , |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado em: |
American Society for Clinical Investigation
2014
|