Targeting triglyceride/fatty acid cycling in β-cells as a therapy for augmenting glucose-stimulated insulin secretion.
Insulin secretion from pancreatic β-cells is triggered by signals arising from the metabolism of glucose and acting through separate initiation and amplification pathways. Despite decades of investigation, crucial details of this mechanism remain poorly understood, especially those relating to the a...
Hlavní autoři: | Cantley, J, Biden, T |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2010
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