Epidermal growth factor receptor signalling contributes to osteoblastic stromal cell proliferation, osteoclastogenesis and disease progression in giant cell tumour of bone.

Epidermal growth factor receptor signalling contributes to osteoblastic stromal cell proliferation, osteoclastogenesis and disease progression in giant cell tumour of bone.

AIMS: Epidermal growth factor receptor (EGFR) is implicated in bone remodelling. The aim was to determine whether EGFR protein expression contributes to the aggressiveness and recurrence potential of giant cell tumour of bone (GCTB), an osteolytic primary bone tumour that can exhibit markedly varia...

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Bibliographic Details
Main Authors: Balla, P, Moskovszky, L, Sapi, Z, Forsyth, R, Knowles, H, Athanasou, N, Szendroi, M, Kopper, L, Rajnai, H, Pinter, F, Petak, I, Benassi, MS, Picci, P, Conti, A, Krenacs, T
Format: Journal article
Language:English
Published: 2011

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