In vitro enzyme assays for JmjC-domain-containing lysine histone demethylases (JmjC-KDMs)

Histone modifications, including lysine methylation marks on histone tails, modulate the accessibility of genes for transcription. Changes in histone tail methylation patterns can cause transcriptional activation or repression. The dynamic regulation of lysine methylation patterns is enabled by two...

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Hlavní autoři: Tarhonskaya, H, Tumber, A, Kawamura, A, Schofield, C
Médium: Journal article
Vydáno: Wiley 2018