Enhancement of MHC class I-restricted peptide-specific T cell induction by a DNA prime/MVA boost vaccination regime.
Human immunodeficiency virus (HIV) vaccine candidates were previously constructed as a string of cytotoxic T lymphocyte (CTL) epitopes delivered and expressed using DNA and modified virus Ankara (MVA; an attenuated vaccinia virus) vectors. These vaccines were shown to induce interferon (IFN)-gamma-p...
Main Authors: | Hanke, T, Blanchard, T, Schneider, J, Hannan, C, Becker, M, Gilbert, S, Hill, A, Smith, G, McMichael, A |
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Format: | Journal article |
Language: | English |
Published: |
1998
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