Long non-coding RNA-derived peptides are immunogenic and drive a potent anti-tumour response
Protein arginine methyltransferase (PRMT) 5 is over-expressed in a variety of cancers and the master transcription regulator E2F1 is an important methylation target. We have explored the role of PRMT5 and E2F1 in regulating the non-coding genome and report here a striking effect on long non-coding (...
Main Authors: | Barczak, W, Carr, SM, Liu, G, Munro, S, Nicastri, A, Lee, LN, Hutchings, C, Ternette, N, Klenerman, P, Kanapin, A, Samsonova, A, La Thangue, NB |
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格式: | Journal article |
语言: | English |
出版: |
Springer Nature
2023
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