Clinical and biological implications of driver mutations in myelodysplastic syndromes.

Clinical and biological implications of driver mutations in myelodysplastic syndromes.

Myelodysplastic syndromes (MDS) are a heterogeneous group of chronic hematological malignancies characterized by dysplasia, ineffective hematopoiesis and a variable risk of progression to acute myeloid leukemia. Sequencing of MDS genomes has identified mutations in genes implicated in RNA splicing,...

全面介紹

書目詳細資料
Main Authors: Papaemmanuil, E, Gerstung, M, Malcovati, L, Tauro, S, Gundem, G, Van Loo, P, Yoon, C, Ellis, P, Wedge, D, Pellagatti, A, Shlien, A, Groves, M, Forbes, SA, Raine, K, Hinton, J, Mudie, L, McLaren, S, Hardy, C, Latimer, C, Della Porta, MG, O'Meara, S, Ambaglio, I, Galli, A, Butler, A, Walldin, G
格式: Journal article
語言:English
出版: 2013

相似書籍