Clinical and biological implications of driver mutations in myelodysplastic syndromes.

Clinical and biological implications of driver mutations in myelodysplastic syndromes.

Myelodysplastic syndromes (MDS) are a heterogeneous group of chronic hematological malignancies characterized by dysplasia, ineffective hematopoiesis and a variable risk of progression to acute myeloid leukemia. Sequencing of MDS genomes has identified mutations in genes implicated in RNA splicing,...

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Bibliographic Details
Main Authors:	Papaemmanuil, E, Gerstung, M, Malcovati, L, Tauro, S, Gundem, G, Van Loo, P, Yoon, C, Ellis, P, Wedge, D, Pellagatti, A, Shlien, A, Groves, M, Forbes, SA, Raine, K, Hinton, J, Mudie, L, McLaren, S, Hardy, C, Latimer, C, Della Porta, MG, O'Meara, S, Ambaglio, I, Galli, A, Butler, A, Walldin, G
Format:	Journal article
Language:	English
Published:	2013

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