Spatial transcriptomic analysis of virtual prostate biopsy reveals confounding effect of tissue heterogeneity on genomic signatures

Genetic signatures have added a molecular dimension to prognostics and therapeutic decision-making. However, tumour heterogeneity in prostate cancer and current sampling methods could confound accurate assessment. Based on previously published spatial transcriptomic data from multifocal prostate can...

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Bibliografiske detaljer
Main Authors: Figiel, S, Yin, W, Doultsinos, D, Erickson, A, Poulose, N, Singh, R, Magnussen, A, Anbarasan, T, Teague, R, He, M, Lundeberg, J, Loda, M, Verrill, C, Colling, R, Gill, PS, Bryant, RJ, Hamdy, FC, Woodcock, DJ, Mills, IG, Cussenot, O, Lamb, AD
Format: Journal article
Sprog:English
Udgivet: BioMed Central 2023