The Antiviral Efficacy of HIV-Specific CD8(+) T-Cells to a Conserved Epitope Is Heavily Dependent on the Infecting HIV-1 Isolate

The Antiviral Efficacy of HIV-Specific CD8(+) T-Cells to a Conserved Epitope Is Heavily Dependent on the Infecting HIV-1 Isolate

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A major challenge to developing a successful HIV vaccine is the vast diversity of viral sequences, yet it is generally assumed that an epitope conserved between different strains will be recognised by responding T-cells. We examined whether an invariant HLA-B8 restricted Nef90-97 epitope FL8 shared...

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Autors principals:	Ranasinghe, S, Kramer, H, Wright, C, Kessler, B, di Gleria, K, Zhang, Y, Gillespie, G, Blais, M, Culshaw, A, Pichulik, T, Simmons, A, Rowland-Jones, S, Mcmichael, A, Dong, T
Format:	Journal article
Idioma:	English
Publicat:	2011

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