Group A streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation

Group A Streptococcus (GAS) infection is associated with multiple clinical sequelae, including different subtypes of psoriasis. Such post-streptococcal disorders have been long known but are largely unexplained. CD1a is expressed at constitutively high levels by Langerhans cells and presents lipid a...

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Hlavní autoři: Chen, Y-L, Ng, JSW, Ottakandathil Babu, R, Woo, J, Nahler, J, Hardman, CS, Kurupati, P, Nussbaum, L, Gao, F, Dong, T, Ladell, K, Price, DA, Duncan, DA, Johnson, D, Gileadi, U, Koohy, H, Ogg, GS
Médium: Journal article
Jazyk:English
Vydáno: American Association for the Advancement of Science 2023