Measurement of plasma 5-hydroxyindoleacetic acid as a possible clinical surrogate marker for the action of antivascular agents.

BACKGROUND: Serotonin (5HT), a naturally occurring vasoactive substance, is released from platelets into plasma under various pathological conditions. Recently, anticancer drugs that act by selectively disrupting tumour blood flow have been found to increase plasma 5HT concentrations in mice. Two su...

詳細記述

書誌詳細
主要な著者: Kestell, P, Zhao, L, Jameson, M, Stratford, MR, Folkes, L, Baguley, B
フォーマット: Journal article
言語:English
出版事項: 2001

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