A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids

The combination of triethylamine, magnesium(II) perchlorate and bipyridine generates a catalyst system for the efficient combination of ethyl isothiocyanatoacetate and a range of aromatic aldehydes. The products of these reactions are synthetically valuable protected β-hydroxy α-amino acids.

Detalles Bibliográficos
Autores principales: Willis, M, Piccio, V
Formato: Journal article
Lenguaje:English
Publicado: 2002
Descripción
Sumario:The combination of triethylamine, magnesium(II) perchlorate and bipyridine generates a catalyst system for the efficient combination of ethyl isothiocyanatoacetate and a range of aromatic aldehydes. The products of these reactions are synthetically valuable protected β-hydroxy α-amino acids.